PfdsaAP eafdfProject A) Titlfdfafe: EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy B) dsfadf: J. Guillermo Paez, Pasi A. JÃ¤nne, Jeffrey C. Lee, Sean Tracy, Heidi Greulich, Stacey Gefdsafeabriel, Paula Herman, Frederic J. Kaye, Neal Lindeman, Titus J. BoggfsaefdfR. Sellers, Bruce E. Johnson, and Matthew Meyerso C) Journal ne: 10.112 E) Page dsafdasf1-8 F) Year: 29 April 2004 G) Paez, J. Guillermo, Pasi A. JÃ¤nne, Jeffrey C. Lee, Sean Tracy, Heidi Greulich, Stacey Gabriel, adHerman, Frederic J. Kaye, Neal Lindeman, Titus J. Boggon, af Naoki, Hidfdadfefumi Sasaki, Yoshitaka Fujii, Michael J. Eck, William R. Sellers, dif eour fdkiedBruce E. Johnson, and Matthew Meyerso EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib. Sciencexpress 10.112 (2004): 1-8. adfdfdas Recepfdfadftor tyrosine kinase genes were sequenced in non small cell lung cancer (f) and matcehdfadfdsfed normal tissue. Somatic revolutions of the cuticular growth factor recedsfdsafdptor gene EGFR were found in 15 of 58 asdfdstumors from Japan fand 1 of 61 from the United States. sermon with dome patients with NffdfadfSCLC.
EGFR mutations were found fin dsaflung cancerdf fsamples frodfdfdm U.S. patients who responded to gefitinib therapy. The results of this experiment were mutations may yell sensitivity to gefitinib. Important Fadfasdfcts * Protein kinase activation by somatic mutation or chromosomal alteration is a common weapon system of tumorigenesis. * Lung dfdfis the leading cause of cancer deaths in the United States and world(a) f or both men and women. * Chemfasfasffad! otherapy for non-small cefdadfall lung carcinoma , which accounts fdaddsfor approximately 8dfdfsfafd5% of lung cancer cases, remains marginally effective.If you want to get a full essay, order it on our website: OrderCustomPaper.com
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